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The price of Axsome Therapeutics, Inc. (AXSM) on October 9, 2026 is 168.81 USD, -0.75% on the day. Over 52 weeks the stock traded between 117.30 USD and 260.19 USD; the price now sits 37% of the way up that range. Over the past year the price changed by +43.36%. Market capitalization is 8.75 billion USD, rank 26 among 374 stocks of the same industry with a known capitalization.
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Next earnings report: 02 November 2026 · Earnings calendar
Axsome Therapeutics, Inc. trades on Nasdaq under the ticker AXSM. The company belongs to the Health care sector. The trading history on this page starts on 22 August 2016.
Over the past 52 weeks AXSM has traded between 117.30 $ and 260.19 $. As of 09 October 2026 the price stood 36.94 % of the way from the 52-week low to the high.
Over one year AXSM shares rose 43.36 %; over six months they fell 4.93 %. Volatility over 90 days is 38.78 %. Dividends are not included: this is price change only, as of 09 October 2026.
The company reported a loss over the last four quarters, so a price-to-earnings ratio is not calculated. Price to sales is 12.3, above the sector median of 3.9. Price to book is 160, above the sector median of 2.4. Calculated from reports for the period ending 31 March 2026.
| Date | Open | High | Low | Close | Volume, shares |
|---|---|---|---|---|---|
| 08 October 2026 | 170.09 | 172.28 | 166.21 | 170.08 | 1M |
| 07 October 2026 | 174.00 | 177.91 | 172.48 | 172.97 | 887,300 |
| 06 October 2026 | 176.52 | 176.52 | 169.30 | 174.34 | 1M |
| 05 October 2026 | 179.25 | 179.70 |
The series is stated in the current share scale after splits; dividends are not included in the price
Based on the last 12 months of reports, through 31 March 2026
The sector median covers every company in the sector on the US market, loss-making ones included.
Axsome develops drugs for the nervous system — depression, narcolepsy, agitation in Alzheimer's disease.
The company's approach is to combine and modify known substances to achieve a new effect with a well-understood safety profile. That is cheaper and faster than searching for a molecule from scratch, but it requires proving the combination is genuinely better than its parts — and patent protection here is more contestable.
Approved drugs for depression and narcolepsy already generate growing revenue, while the main bet is agitation in Alzheimer's disease, a condition with essentially no approved treatment and an enormous burden on carers. Risks: patent disputes with generic makers, trial outcomes and reimbursement. The company pays no dividend.
Address:ONE WORLD TRADE CENTER, 29TH FLOOR, NEW YORK, NY, 10007, US
Axsome Therapeutics, Inc. reported revenue of 708M $ and a net loss of 188M $ over the last four quarters. Net margin is −26.59 %. Revenue changed by +63.88 % year over year. Earnings per share are −3.72 $. Market capitalisation is 8.7B $.
AXSM has a return on equity of −344.96 %, below the sector median of −41.68 %. Return on assets is −26.39 %, above the sector median of −32.11 %. Operating margin is −24.45 %, above the sector median of −26.84 %.
| 1.2B |
| PFEPfizer, Inc. | 28.18 | +1.28 % | 929M |
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| BMYBristol-Myers Squibb Company | 59.12 | −0.77 % | 714M |
| REGNRegeneron Pharmaceuticals, Inc. | 746.54 | +0.94 % | 555M |
| 175.73 |
| 177.08 |
| 858,900 |
| 02 October 2026 | 182.55 | 182.55 | 175.46 | 179.25 | 981,400 |
| 01 October 2026 | 184.39 | 185.67 | 181.75 | 182.07 | 660,200 |
| 30 September 2026 | 186.51 | 188.00 | 184.00 | 184.39 | 1M |
| 29 September 2026 | 191.41 | 194.25 | 182.10 | 186.14 | 2M |
| 28 September 2026 | 194.98 | 198.96 | 193.11 | 193.89 | 707,400 |
| 25 September 2026 | 197.68 | 201.42 | 194.35 | 195.09 | 838,200 |
| 24 September 2026 | 193.02 | 197.11 | 190.72 | 196.03 | 386,100 |
| 23 September 2026 | 204.01 | 204.70 | 189.05 | 193.45 | 913,000 |
| 22 September 2026 | 205.68 | 207.01 | 202.52 | 203.10 | 299,800 |
| 21 September 2026 | 208.17 | 210.85 | 203.38 | 205.49 | 543,500 |
| 18 September 2026 | 212.05 | 213.27 | 206.92 | 207.78 | 869,300 |
| 17 September 2026 | 215.59 | 216.47 | 208.63 | 214.28 | 681,400 |
| 16 September 2026 | 202.95 | 214.64 | 201.94 | 211.97 | 644,900 |
| 15 September 2026 | 215.02 | 215.02 | 203.78 | 204.07 | 591,300 |
| 14 September 2026 | 221.93 | 223.29 | 216.00 | 216.58 | 718,800 |
| 11 September 2026 | 212.71 | 229.62 | 212.44 | 220.75 | 1M |